Excessive Pretreatment Weight Loss Is a Risk Factor for the Survival Outcome of Esophageal Carcinoma Patients Undergoing Radical Surgery and Postoperative Adjuvant Chemotherapy

Autor: Xiao-Li Yu, Jin Yang, Ting Chen, Yi-min Liu, Wei-ping Xue, Ming-Hui Wang, Shou-Min Bai
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Canadian Journal of Gastroenterology and Hepatology, Vol 2018 (2018)
Druh dokumentu: article
ISSN: 2291-2789
2291-2797
DOI: 10.1155/2018/6075207
Popis: Background. The prognostic values of weight loss and body mass index (BMI) in esophageal carcinoma remain controversial. This study aimed to evaluate the impacts of weight loss on the survival of patients undergoing radical surgery and adjuvant chemotherapy. Methods. The medical records of 189 consecutive patients with nonmetastatic esophageal carcinoma treated in our hospital between January 2012 and December 2013 were reviewed, and 121 patients were included for analysis. Results. Kaplan-Meier analysis revealed that the 3-year overall survival rate was significantly higher in the low pretreatment weight loss (pre-LWL) group than in the high pretreatment weight loss (pre-HWL) group (P
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