| Autor: |
Keishi Kishimoto, Kana T. Furukawa, Agustin Luz-Madrigal, Akira Yamaoka, Chisa Matsuoka, Masanobu Habu, Cantas Alev, Aaron M. Zorn, Mitsuru Morimoto |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-17969-w |
| Popis: |
How murine tracheal mesenchyme is specified during development is unclear. Here, the authors show a Wnt pathway target, Tbx4, is needed but this is regulated by Wnt signals from neighbouring tracheal epithelial cells, and take advantage of this knowledge to generate tracheal cartilage and smooth muscle on dish from mouse and human embryonic stem cells. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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