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Khaled Alzahrani,1–3 Hanan Mofty,1,4 Emily YC Lin,1 Fiona Carley,2 Arun Brahma,2 Debbie Morley,2 Susmito Biswas,2 M Chantal Hillarby1 1Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester, UK; 2Research Department, Manchester Royal Eye Hospital, Manchester, UK; 3King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia; 4Optometry Department, College of Applied Medical Science, King Saud University, Riyadh, Kingdom of Saudi ArabiaCorrespondence: Khaled AlzahraniOptometry Division, Opthalmology Department, King Fahad Armed Forces Hospital, P O Box 986, Jeddah 21159, Saudi ArabiaEmail khaledod@gmail.comPurpose: In this study densitometry software for the Oculus Pentacam was used to investigate the treatment outcomes of corneal cross linking (CXL) in adult and juvenile keratoconus (KCN) patients. Densitometry measurements were taken before and after treatment and followed up for one year.Methods: A comparative study was carried out at Manchester Royal Eye Hospital. Corneal densitometry measurements collected before and after CXL treatment for 32 eyes from KC patients, aged between 12 and 39, were divided to 2 groups 13–18 years (juvenile group) and 19–39 years (adult group) and analysed and compared to pre and post treatment at 3, 6 and 12 months for each group and between both groups.Results: Analysis of densitometry measurements found higher corneal densitometry after CXL which peaks at three months post treatment in both groups. There was significant diversity in corneal densitometry measurements in the stromal zone 0–2 and 2–6 mm for all layers except the posterior layer for both groups (P |
