Survival in severe pulmonary hypertension due to chronic lung disease: influence of in-hospital platelet distribution width

Autor: Lan Wang, Li Shen, Ya-Lin Zhao, Bigyan Pudasaini, Qin-Hua Zhao, Su-Gang Gong, Rui Zhang, Ping Yuan, Jing He, Ci-Jun Luo, Hong-Ling Qiu, Jin-Ming Liu, Rong Jiang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Pulmonary Circulation, Vol 11 (2021)
Druh dokumentu: article
ISSN: 2045-8940
20458940
DOI: 10.1177/20458940211026484
Popis: Platelet distribution width has been recognized as risk predictors of idiopathic pulmonary arterial hypertension. This study aims to investigate whether in-hospital platelet distribution width would be useful to predict all-cause death in patients with severe pulmonary hypertension due to chronic lung diseases (CLD-PH). Early in-hospital platelet distribution width was measured in 67 severe CLD-PH patients who were confirmed by right heart catheterization and followed up. Event-free survival was estimated using the Kaplan–Meier method and analyzed with the log-rank test. Cox proportional hazards models were performed to determine the association between the platelet distribution width level and all-cause death. During median of 2.4 (2.5, 3.7) years of follow-up, 44 patients died. A significant association was noted between in-hospital platelet distribution width level and the adjusted risk of all-cause mortality (hazard ratio: 1.245; 95% confidence interval: 1.117–1.386, P
Databáze: Directory of Open Access Journals
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