ROS induced lipid peroxidation and their role in ferroptosis

Autor: Hiwot Tezera Endale, Winta Tesfaye, Tiget Ayelgn Mengstie
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2296-634X
DOI: 10.3389/fcell.2023.1226044
Popis: Reactive oxygen species (ROS) play a crucial part in the process of cell death, including apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate 4-hydroxynonenal and other compounds associated with it. Ferroptosis may be facilitated by lipid peroxidation of phospholipid bilayers. In order to offer novel ideas and directions for the investigation of disorders connected to these processes, we evaluate the function of ROS in lipid peroxidation which ultimately leads to ferroptosis as well as proposed crosstalk mechanisms between ferroptosis and other types programmed cell death.
Databáze: Directory of Open Access Journals