Cryo-EM structure supports a role of AQP7 as a junction protein

Autor: Peng Huang, Raminta Venskutonytė, Rashmi B. Prasad, Hamidreza Ardalani, Sofia W. de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Gourdon, Isabella Artner, Karin Lindkvist-Petersson
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36272-y
Popis: Glycerol flux across the plasma membrane is critical to metabolism and linked to disease. Here, authors present the cryo-EM structure of the glycerol channel AQP7 composed of two adhering tetramers and displaying well-defined densities in the central pore.
Databáze: Directory of Open Access Journals