Experimental validation that human microbiome phages use alternative genetic coding

Autor: Samantha L. Peters, Adair L. Borges, Richard J. Giannone, Michael J. Morowitz, Jillian F. Banfield, Robert L. Hettich
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-32979-6
Popis: Previous bioinformatic analyses have indicated that bacteriophages can use genetic codes different from those of their host bacteria. Here, Peters et al. use metaproteomics to provide experimental evidence of reassignment of stop codon TAG to glutamine in phages found in the human gut microbiome.
Databáze: Directory of Open Access Journals