Differential Diagnosis of Hepatic Mass with Central Scar: Focal Nodular Hyperplasia Mimicking Fibrolamellar Hepatocellular Carcinoma

Autor: Teodoro Rudolphi-Solero, Eva María Triviño-Ibáñez, Antonio Medina-Benítez, Javier Fernández-Fernández, Daniel José Rivas-Navas, Alejandro José Pérez-Alonso, Manuel Gómez-Río, Tarik Aroui-Luquin, Antonio Rodríguez-Fernández
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Diagnostics, Vol 12, Iss 1, p 44 (2021)
Druh dokumentu: article
ISSN: 2075-4418
DOI: 10.3390/diagnostics12010044
Popis: Fibrolamellar hepatocellular carcinoma is a primary hepatic tumor that usually appears in young adults. Radical surgery is considered curative for this kind of tumor, so early diagnosis becomes essential for the prognosis of the patients. The main characteristic of this entity is the central scar, which is the center of differential diagnosis. We report the case of a 30-year-old man who was diagnosed with fibrolamellar hepatocellular carcinoma by ultrasonography. Contrast-enhanced CT confirmed this diagnosis, and the patient underwent a [18F] fluorocholine PET/CT. Hypermetabolism and the morphology in the nuclear medicine exploration suggest neoplastic nature of the lesion. Radical surgery was performed, and histopathologic analysis was performed, which resulted in focal nodular hyperplasia. Hepatic masses with central scar could have a difficult differential diagnosis, and focal nodular hyperplasia could mimic fibrolamellar hepatocellular carcinoma imaging patterns. These morphofunctional characteristics have not been described in [18F] Fluorocholine PET/CT, so there is a need to find out the potential role PET/CT in the differential diagnosis of hepatic mass with central scar.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje