Autor: |
Yu Wang, Fabiana Subrizi, Eve M. Carter, Tom D. Sheppard, John M. Ward, Helen C. Hailes |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-022-33122-1 |
Popis: |
Pharmaceuticals derived from benzylisoquinoline alkaloids find application in modern medicine. Here, the authors report the design of a parallel enzymatic cascade to generate halogenated benzylisoquinoline alkaloids, that included engineering of tyrosinase mutants to enhance substrate capabilities. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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