Autor: |
Mateusz Jurga, Arwa A. Abugable, Alastair S. H. Goldman, Sherif F. El-Khamisy |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-021-25459-w |
Popis: |
DNA:RNA hybrids (R-loops) are products of transcription that impact genome integrity and gene expression. Here the authors reveal a mechanism for regulating R-loops in a ubiquitination-dependent manner controlled by the activities of USP11 and KEAP1 |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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