Considerations on the use of Humulus lupulus L. as an estrogenic agent
| Autor: | Anca Daniela RAICIU, Daniel CORD, Alin FOCŞA |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Romanian Journal of Medical Practice, Vol 12, Iss 4, Pp 198-203 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1842-8258 2069-6108 |
| DOI: | 10.37897/RJMP.2017.4.4 |
| Popis: | Introduction. Hops (Humulus lupulus L.) is used as a raw material for the production of beer but has also biological properties. Phytoestrogens present in the hops have an antioxidant, anti-inflammatory and probiotic role, while having an effect on the diseases of osteoporosis, diabetes and vasomotor effects (calf) during menopause. Material and method. 8-prenilnaringenine was prepared according to a modification of the initial method. To a cooled solution of naringenin was added a methanolic sodium methoxide solution and prenyl bromide. Results and discussions. The estrogenic effect has been attributed to substances such as β-acids, β-sitosterol, xanthohumol and desmethylxanthohumol. Further investigations have shown that 8-prenylnaringenine is a major hops estrogen. 8-prenilnaringenin acts on estrogen receptors that mediate bone osteoblastic formation and inhibit osteoclastic bone resorption. |
| Databáze: | Directory of Open Access Journals |
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