| Autor: |
Natália Rangel Palmier, Bruno Augusto Linhares Almeida Mariz, Letícia Rodrigues-Oliveira, Karina Morais-Faria, César Augusto Migliorati, Luiz Paulo Kowalski, Karina Moutinho, Thaís Bianca Brandão, Alan Roger Santos-Silva, Ana Carolina Prado-Ribeiro |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Oral Oncology Reports, Vol 9, Iss , Pp 100185- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2772-9060 |
| DOI: |
10.1016/j.oor.2024.100185 |
| Popis: |
Aims: To assess the patterns of radiotherapy-induced dysgeusia among oral and oropharyngeal squamous cell carcinoma (OOSCC) patients subjected to different oncological treatment modalities. Patients and methods: OOSCC patients who underwent head and neck radiotherapy (HNRT) or chemoradiotherapy (CRT). Patients were paired in 8 groups divided by primary treatment (surgery or induction CT) followed by CRT or HNRT and definitive treatment with CRT or HNRT. Dysgeusia, xerostomia, oral mucositis (OM) grades and tube feeding information were retrieved from electronic medical charts. Statistical analysis was performed regarding the correlation of treatment modalities with dysgeusia, and of xerostomia and OM with dysgeusia. Results: 150 patients were included. Over 90 % of patients developed dysgeusia during HNRT. Groups that included CRT presented early severe dysgeusia. Tongue surgery followed by CRT presented grade 2 at 10Gy when compared to HNRT (p = 0.04), groups with other surgery (such as mandibulectomy) or induction CT followed by CRT presented more grade 2 dysgeusia at 40Gy of HNRT (p = 0.04). Xerostomia and dysgeusia grades and OM and dysgeusia grades presented a positive correlation (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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