| Autor: |
Xin-Fei Chen, Wei Zhang, Xin Fan, Xin Hou, Xiao-Yu Liu, Jing-Jing Huang, Wei Kang, Ge Zhang, Han Zhang, Wen-Hang Yang, Ying-Xing Li, Jin-Wen Wang, Da-Wen Guo, Zi-Yong Sun, Zhong-Ju Chen, Ling-Gui Zou, Xue-Fei Du, Yu-Hong Pan, Bin Li, Hong He, Ying-Chun Xu |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2235-2988 |
| DOI: |
10.3389/fcimb.2021.739496 |
| Popis: |
Diutina catenulata (Candida catenulata) is an ascomycete yeast species widely used in environmental and industrial research and capable of causing infections in humans and animals. At present, there are only a few studies on D. catenulata, and further research is required for its more in-depth characterization and analysis. Eleven strains of D. catenulata collected from China Hospital Invasive Fungal Surveillance Net (CHIF-NET) and the CHIF-NET North China Program were identified using matrix-assisted laser desorption ionization–time of flight mass spectrometry and internal transcribed spacer sequencing. The antifungal susceptibility of the Diutina catenulata strains was tested using the Clinical and Laboratory Standards Institute broth microdilution method and Sensititre YeastOne™. Furthermore, ERG11 and FKS1 were sequenced to determine any mutations related to azole and echinocandin resistance in D. catenulata. All isolates exhibited low minimum inhibitory concentration (MIC) values for itraconazole (0.06–0.12 μg/ml), posaconazole (0.06–0.12 μg/ml), amphotericin B (0.25–1 μg/ml), and 5-flucytosine (range, |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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