Effectiveness of Thermostable Vaccine for Newcastle Disease Produced by the Razi Institute on Backyard Poultry in Iran during 2015
| Autor: | M.H. Fallah Mehrabadi, S.A. Ghafouri, A. Shoushtari, F. Tehrani, S. Masoudi, M. Abdoshah, S. Amir Hajloo, M. Shabani |
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| Jazyk: | English<br />French |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Archives of Razi Institute, Vol 75, Iss 1, Pp 1-7 (2020) |
| Druh dokumentu: | article |
| ISSN: | 0365-3439 2008-9872 |
| DOI: | 10.22092/ari.2018.120709.1199 |
| Popis: | Newcastle disease causes many economic losses to the poultry industry in most countries. This disease is endemic in Iran. Backyard poultry is considered the reservoir of Newcastle virus; however, there is either no vaccination program against Newcastle, or it is performed in a restricted manner. Commercial live vaccines are inactive and sensitive to temperature; moreover, vaccine delivery to villages and remote areas requires special equipment and high cost to maintain the cold chain. This study evaluated the effectiveness of a thermostable Newcastle vaccine produced by the Razi Institute (ND.TR.IR) on the backyard poultry. In four provinces, at least 4 villages were selected as the treatment group, and the same number was selected as the control group. At least, 30 birds were sampled in each village. In each group, blood samples were collected before vaccination and 2 weeks later, and the serum titer of the samples was examined with the haemagglutination inhibition test. The arithmetic mean and standard deviation of the sample titers at the rural level were compared using paired t-test before and after vaccination in each group. Moreover, Repeated Measures ANOVA was utilized to compare the vaccinated and control groups in terms of the titer changes before and after vaccination. In this study, 584 and 389 samples were taken from the treatment (53 households in 20 villages) and control groups (33 households in 14 villages). The mean serum titer values of Newcastle were 4.51±3.03 and 6.64±2.48 in the treatment group before and after vaccination, respectively (P |
| Databáze: | Directory of Open Access Journals |
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