Lifespan prolonging mechanisms and insulin upregulation without fat accumulation in long-lived reproductives of a higher termite

Autor: Sarah Séité, Mark C. Harrison, David Sillam-Dussès, Roland Lupoli, Tom J. M. Van Dooren, Alain Robert, Laure-Anne Poissonnier, Arnaud Lemainque, David Renault, Sébastien Acket, Muriel Andrieu, José Viscarra, Hei Sook Sul, Z. Wilhelm de Beer, Erich Bornberg-Bauer, Mireille Vasseur-Cognet
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-02974-6
Popis: Séité, Harrison, et al. investigate the mechanisms underlying long lifespan in queens and kings of the highly social termite Macrotermes natalensis. Using transcriptomics, lipidomics and metabolomics, this study shows that several aging-related processes are reduced in the fat bodies of these reproductives and that an upregulated insulin-like peptide, Ilp9, does not lead to deleterious fat storage in old queens, while simple sugars dominate in their hemolymph.
Databáze: Directory of Open Access Journals
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