Discovery and analysis of a new class of triterpenes derived from hexaprenyl pyrophosphate

Autor: Dan Hu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Engineering Microbiology, Vol 2, Iss 3, Pp 100035- (2022)
Druh dokumentu: article
ISSN: 2667-3703
DOI: 10.1016/j.engmic.2022.100035
Popis: Triterpenes are derived from squalene or oxidosqualene. However, a new class of triterpenes derived from hexaprenyl pyrophosphate has been recently discovered, formed by a new family of chimeric class I triterpene synthases. The cyclization mechanisms of triterpenes were elucidated by isotopic labeling and protein structural analyses, which helps understand the biosynthesis of triterpenes in nature.
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