Idarubicin-loaded drug-eluting microspheres transarterial chemoembolization for intermediate stage hepatocellular carcinoma: safety, efficacy, and pharmacokinetics

Autor: Korsic Spela, Osredkar Josko, Smid Alojz, Steblovnik Klemen, Popovic Mark, Locatelli Igor, Trontelj Jurij, Popovic Peter
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Radiology and Oncology, Vol 58, Iss 4, Pp 517-526 (2024)
Druh dokumentu: article
ISSN: 1581-3207
DOI: 10.2478/raon-2024-0052
Popis: Transarterial chemoembolization (TACE) is the treatment of choice for the intermediate stage hepatocellular carcinoma (HCC). Doxorubicin remains the most used chemotherapeutic agent in TACE, although in vitro screening has demonstrated that idarubicin exhibits greater cytotoxicity against HCC. This study aimed to evaluate safety, efficacy, and pharmacokinetics of idarubicin-loaded drug-eluting microspheres TACE (DEMIDA-TACE) in intermediate stage HCC patients.
Databáze: Directory of Open Access Journals