Frequency and Pattern of Thyroid Dysfunction in Patients with Polycystic Ovary Syndrome

Autor: Sadaf Naz, khurshid Ahmad khan, Amina Umer, Muhammad Tabish Raza, Khalid Mehmood Nasir, Imtiaz Hussain
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Pakistan Armed Forces Medical Journal, Vol 72, Iss 5 (2022)
Druh dokumentu: article
ISSN: 0030-9648
2411-8842
DOI: 10.51253/pafmj.v72i5.3288
Popis: Objective: To determine the frequency and pattern of thyroid dysfunction in patients with polycystic ovary syndrome. Study Design: Cross-sectional study. Place and Duration of Study: Department of Endocrinology, Jinnah Hospital, Lahore Pakistan, from Jan from Jun 2017. Methodology: Seventy-seven patients diagnosed with PCOS, based on Rotterdam criteria, were enrolled in the study. Thyroid function status was evaluated using measurement of serum thyroid-stimulating hormone (TSH), free T3, T4 and anti-thyroperoxidase (anti-TPO) antibodies. Results: The mean age of the study population was 29.0±9.2 years. Out of 77 females with PCOS, 63(81.8%) were euthyroid, five (6.5%) patients were diagnosed with primary hypothyroidism, and nine (11.7%) were found to have subclinical hypothyroidism. Anti-TPO antibodies were detected in 18 patients (23.4%), including 12(19.0%) euthyroid females. Conclusion: Thyroid dysfunction was found among patients with PCOS. Evidence of autoimmunity was seen even in euthyroid patients.
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