Impact evaluation of guidelines on antibiotic utilisation & appropriateness in Malaysian public primary care: an interrupted time series analysis
| Autor: | Audrey Huili Lim, Norazida Ab Rahman, Su Miin Ong, Siti Raidah Mohamad Azman, Fairus Zana Mohd Rathi, Mastura Ismail, Peter Seah Keng Tok, Bee Kiau Ho, Sheamini Sivasampu |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Pharmaceutical Policy and Practice, Vol 17, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 20523211 2052-3211 |
| DOI: | 10.1080/20523211.2024.2355666 |
| Popis: | Background: The National Antimicrobial Guidelines (NAG) 2014 and NAG2019 in Malaysia targeted rational and judicious use of antimicrobials. In this study, we assessed the change in antibiotic utilisation and appropriateness due to the guidelines that were implemented from 2011 to 2019.Methods: Interrupted time series analyses on rates of antibiotic appropriateness and utilisation were performed using prescription data from public primary care clinics in Malaysia between January 2011 and December 2019. Rates of antibiotic utilisation, reported as Defined Daily Dose (DDD) per 1000 patients per day, were stratified by antibiotic classes.Results: Of the 16,081,492 prescriptions recorded during the study period, 4.98% (n = 800,899) contained antibiotics. NAG2014 resulted in a significant increase in antibiotic utilisation trend by 0.029 (p |
| Databáze: | Directory of Open Access Journals |
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