The Association between Cobalt Deficiency and Endemic Goiter in School-Aged Children
| Autor: | Mojgan Sanjari, Ahmad Gholamhoseinian, Akram Nakhaee |
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| Jazyk: | English<br />Korean |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Endocrinology and Metabolism, Vol 29, Iss 3, Pp 307-311 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2093-596X 2093-5978 |
| DOI: | 10.3803/EnM.2014.29.3.307 |
| Popis: | BackgroundIn Iran, an iodine deficiency control program was initiated in 1989 by iodizing salt. Despite this program, goiters have remained an endemic condition in most parts of Iran. Thus, it is possible that other factors aside from iodine deficiency may contribute to endemic goiter. The aim of this study was to investigate the association between cobalt deficiency and endemic goiter in a region of Iran with a high prevalence of goiter.MethodsA cross-sectional study was conducted among school children aged 9 to 11 years in the city of Kerman, Iran. In the first phase of the study, a multistage, proportional-to-size, cluster sampling method was used to screen 5,380 out of 29,787 students. After the screening phase, 170 students (130 goitrous and 40 nongoitrous) were randomly selected, and serum and urine specimens were obtained. We measured thyroid function, serum cobalt level, and urinary iodine excretion. Univariate and multiple logistic regression analyses were performed.ResultsThe prevalence of grade 2 goiters was 34.8% (95% confidence interval [CI], 31.5 to 42.5), with both sexes being equally affected. The weight and body mass index of goitrous subjects was significantly lower (P |
| Databáze: | Directory of Open Access Journals |
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