Hypercortisolism on the background of recovery of COVID-19 (сase report)
| Autor: | V. Kravchenko, O. Rakov, L.V. Slipachuk |
|---|---|
| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Mìžnarodnij Endokrinologìčnij Žurnal, Vol 18, Iss 2, Pp 133-137 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2224-0721 2307-1427 |
| DOI: | 10.22141/2224-0721.18.2.2022.1159 |
| Popis: | Damage to the lung tissue is a predominant complication of the viral disease COVID-19. Recently, there have been complications from other organs, including highly vascularized endocrine glands. Regarding the adrenal glands, there are reports of their damage with a decrease in their function. Сhanging the function of the adrenal glands (AG) in patients with or after COVID-19 is important. A few adrenal autopsy studies in patients have revealed vascular thrombosis, cortical lipid degeneration, ischemic necrosis, parenchymal infarcts, and other lesions leading to a decrease in AG function. The central mechanism of adrenal dysfunction through hemorrhage and necrosis of the pituitary gland is also possible. This paper presents a rare case of the development of hypercortisolism in a young woman after recovering from COVID-19. Based on high ACTH levels (157 and 122 pg/ml), a negative nocturnal dexamethasone test, and high 24-hour urinary free (daily) cortisol excretion rates, we tentatively suspected Cushing’s disease. Chromogranin A was within the normal range of 21.35 (reference value |
| Databáze: | Directory of Open Access Journals |
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