Dose Adjustment of Subcutaneous IgG in Chronic Inflammatory Demyelinating Polyneuropathy

Autor: Alanood Alsolaihim, Steven K. Baker
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Case Reports in Neurology, Vol 12, Iss 1, Pp 73-77 (2020)
Druh dokumentu: article
ISSN: 1662-680X
DOI: 10.1159/000505320
Popis: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated neuropathy that is characterized by a slowly progressive sensory and motor involvement lasting at least 2 months. We present a CIDP patient on subcutaneous Ig (SCIg). Upon fine-tuning his dose from 24 to 28 g/week, this showed a dramatic improvement in both hand grip (13–25%) and dorsiflexion (73–278%). Follow-up nerve conduction studies also demonstrated significant improvements in latencies, motor amplitudes, and conduction velocities. Ongoing surveillance of CIDP patients receiving SCIg therapy is therefore necessary to ensure therapeutic optimization.
Databáze: Directory of Open Access Journals