| Autor: |
Florine Essouman Mbappe, Ferdinand Lanvin Edoun Ebouel, Fils Armand Ella, Bruno Dupon Ambamba Akamba, Jules Kamga Nanhah, Innocent Gouado, Judith Laure Ngondi |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Metabolism Open, Vol 13, Iss , Pp 100156- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2589-9368 |
| DOI: |
10.1016/j.metop.2021.100156 |
| Popis: |
Introduction: Beilschmiedia (Lauraceae) is a pantropical genus of about 287 species, distributed in tropical Asia and Africa used in traditional medicines to cure many diseases. This study aimed to explore biological properties of Beilschmiedia obscura (B. obscura) on the prevention and management of metabolic syndrome (MetS) features induced by High Fat/High Sucrose (HF/HS) diet in rats as therapeutic option. Methods: MetS was induced after administration of HF/HS diet followed by administration of B. Obscura powder at 5% or 10% for 21 days, while the control group received a chow diet and distilled water and the positive control group received the HF/HS diet and distilled water. At the end of the experiment, rats were sacrificed; the parameters of lipid profile, markers of oxidative stress, antioxidant status were evaluated. Results: HF/HS diet successfully induced weight gain, oxidative stress and lipid profile disorders from rats. Treatment with powder of B. obscura at 10% than the 5% showed a reduction of body weight in treated groups and, anti-hyperlipidemic effect by improving lipid profile parameters. Triglycerides, Total cholesterol and LDL cholesterol levels were lower (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
