Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation
| Autor: | Julián Alejandro Rivillas, Stephania Galindo-Coral, Francisco Arias-Mora, Juan David Lopez-Ponce de Leon, Noel Alberto Florez-Alarcón, Pastor Olaya-Rojas, Juan Esteban Gomez-Mesa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Case Reports in Cardiology, Vol 2021 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2090-6404 2090-6412 |
| DOI: | 10.1155/2021/9998205 |
| Popis: | Background. Neurological complications occur between 50 and 70% of patients with heart transplantation, including cerebrovascular events, infections, seizures, encephalopathy, and neurotoxicity due to pharmacological immunosuppression. Mortality associated with cerebrovascular complications is 7.5% in the first 30 days and up to 5.3% after the first month and up to the first year after transplantation. Case Reports. Three heart-transplanted patients (2 men and 1 woman) treated with tacrolimus were identified. They presented with posterior reversible encephalopathy syndrome on days 5, 6, and 58 posttransplantation, respectively. In these reported cases, no sequelae were observed at 6 months follow-up. Conclusions. Posterior reversible encephalopathy syndrome as a neurological complication in patients with HT occurred early after the procedure. Early diagnosis and treatment might reduce the risk of serious complications and mortality. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|