Measurements of Serum Pituitary-Gonadal Hormones and Investigation of Sexual and Reproductive Functions in Kidney Transplant Recipients

Autor: Guang-chun Wang, Jun-hua Zheng, Long-gen Xu, Zhi-lian Min, You-hua Zhu, Jun Qi, Qiang-lin Duan
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: International Journal of Nephrology, Vol 2010 (2010)
Druh dokumentu: article
ISSN: 2090-2158
DOI: 10.4061/2010/612126
Popis: Objective. To investigate changes in serum pituitary-gonadal hormones and restoration of sexual and reproductive functions after successful kidney transplantation. Patients and Methods. Serum pituitary-gonadal hormones before and after kidney transplantation were measured in 78 patients with end-stage renal disease (ESRD) and in 30 healthy adults. Pre- and postoperative semen specimens of 46 male recipients and 15 male controls were collected and compared. Additional 100 married kidney transplant recipients without children were followed up for 3 years to observe their sexual function and fertility. Results. Serum PRL, LH, and T or E2 levels gradually restored to the normal ranges in all kidney transplant recipients, and sperm density, motility, viability, and morphology significantly improved in the male recipients 4 months after successful kidney transplantation (P
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