Predictor of Death in Diarrheal Children Under 5 Years of Age Having Severe Sepsis in an Urban Critical Care Ward in Bangladesh

Autor: Monira Sarmin MBBS, MCPS, Farzana Afroze MBBS, FCPS, Sharifuzzaman MBBS, Tahmina Alam MBBS, Nusrat Jahan Shaly MBBS, Tahmeed Ahmed MBBS, PhD, Mohammod Jobayer Chisti MBBS, MMed, PhD
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Global Pediatric Health, Vol 6 (2019)
Druh dokumentu: article
ISSN: 2333-794X
2333794X
DOI: 10.1177/2333794X19862716
Popis: We aimed to identify clinical predictors of fatal outcome in children under 5 years of age having diarrhea and severe sepsis and treated in the Intensive Care Unit of the Dhaka Hospital of icddr,b from October 2010 through September 2011. Among 191 enrolled children, 70 (37%) died and were considered to be cases, while the remaining 121 (63%) who survived constituted the controls. The cases more often had shortness of breath (SOB), septic shock, dehydrating diarrhea compared with the controls (for all, P < .05). After adjusting for potential confounders using logistic regression analysis, the likelihood of death was higher in children who had septic shock and SOB and lower in children having dehydrating diarrhea (for all, P < .05). Thus, SOB can trigger an early alarm for sepsis recognition; otherwise, these children can end up with fatality from septic shock. In resource-poor settings, early identification of these predictors can alleviate death.
Databáze: Directory of Open Access Journals