Genetic factors in the development of pulmonary embolism

Autor:	N. M. Kryuchkova, A. A. Chernova, S. Yu. Nikulina, V. N. Maksimov
Jazyk:	ruština
Rok vydání:	2022
Předmět:	pulmonary embolism gene factor v leiden mutation genotype polymorphism f2 f5 pai itga2 Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Российский кардиологический журнал, Vol 27, Iss 10 (2022)
Druh dokumentu:	article
ISSN:	1560-4071 2618-7620
DOI:	10.15829/1560-4071-2022-5173
Popis:	The article presents a literature review on the study of the relationship of FGA, FGB, F2, F5, PAI, ITGA2 gene polymorphisms with the development of pulmonary embolism (PE). We concluded that genetic factors in the development of PE are to a greater extent mutations in the F2, F5, PAI, ITGA2 genes. There is a positive correlation between the presence of combined genetic mutations and the development of PE. The study of allelic polymorphism of hemostasis genes makes it possible to predict coagulation system disorders, including PE.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/b015c0ee5db6449f94604eb6c3529106 Zobrazit plný text záznamu View record in DOAJ