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Background. The microelemental composition of the heart wall has been studied at an inadequate level, which requires modern, fundamental cardiology. In particular, the literature does not sufficiently study regional features of not only quantitative content, but also the ratio of bioelements in the cardiac muscle, which is important for understanding asynchronous heart rate in normal and in pathology. Objective. The aim of the study was to establish differences in mineral composition in the wall of the human heart during ontogenesis. Methods. 36 hearts of people of different age groups were studied using atomic absorption spectrophotometry. Results. As a result of studying the chemical composition of the human myocardium during ontogenesis, there were both age and regional differences. Comparing the quantitative composition of bioelements, in the hearts of the fetuses and in the hearts of infants, a significant increase in Ca, Zn, Cu concentration was identified. The amount of Mg was significantly higher in the right atrial wall, the maximum concentration of Ca was contained in the right ventricle. Zn also had same tendencies. Cu was characterized by a reverse tendency. Conclusion. As the age increases, there are statistically significant changes in the content of macro- and microelements in the wall of the heart. The results obtained testify to a change in the chemical composition of the myocardium, not only in the age aspect, but also in the regional one. The quantitative composition of bioelements in the right ventricle in a human in adulthood testifies, on the one hand, of their hyperfunction associated with complications of blood flow in a small circle of blood circulation in connection with the development of age-related emphysema of the lungs, and on the other hand - the involution of the physiological processes that occur in the wall of the heart . |
