| Autor: |
Fahir Özkalemkaş, Vildan Ozkocaman, Bedrettin Orhan, Ömer Candar, İbrahim Ethem Pınar, Tuba Ersal, Cumali Yalçın |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Turkish Journal of Internal Medicine, Vol 3, Iss Supplement 1, Pp 40-41 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2687-4245 |
| DOI: |
10.46310/tjim.877049 |
| Popis: |
Nodular lymphocyte predominant Hodgkin lymphoma is an infrequent disease. It is associated with a favorable prognosis. The most important problems with the management of the disease are relapses, transformation to non-Hodgkin lymphoma, and treatment-related toxicities. In early stages of disease, watchful waiting, surgery, radiotherapy, and single-agent rituximab are the treatment options. Chemo-immunotherapy may be preferred in early disease with high tumor and symptom burden. In advanced disease, chemo-immunotherapy with or without radiotherapy is used. Good responses can be achieved in relapsed disease. The risk of transformation is high. It is reasonable to obtain re-biopsies at relapses. Transformed disease and the primary disease have been shown to be clonally-related in most cases. Prognosis of transformed disease which is treated with salvage chemo-immunotherapy followed by autologous stem cell transplantation is similar to that of de novo diffuse large B-cell lymphoma. All of the data regarding the treatment come from retrospective data. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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