Modulation of Crystallinity through Radiofrequency Electromagnetic Fields in PLLA/Magnetic Nanoparticles Composites: A Proof of Concept

Autor: Marta Multigner, Irene Morales, Marta Muñoz, Victoria Bonache, Fernando Giacomone, Patricia de la Presa, Rosario Benavente, Belén Torres, Diego Mantovani, Joaquín Rams
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Materials, Vol 14, Iss 15, p 4300 (2021)
Druh dokumentu: article
ISSN: 1996-1944
DOI: 10.3390/ma14154300
Popis: To modulate the properties of degradable implants from outside of the human body represents a major challenge in the field of biomaterials. Polylactic acid is one of the most used polymers in biomedical applications, but it tends to lose its mechanical properties too quickly during degradation. In the present study, a way to reinforce poly-L lactic acid (PLLA) with magnetic nanoparticles (MNPs) that have the capacity to heat under radiofrequency electromagnetic fields (EMF) is proposed. As mechanical and degradation properties are related to the crystallinity of PLLA, the aim of the work was to explore the possibility of modifying the structure of the polymer through the heating of the reinforcing MNPs by EMF within the biological limit range f·H < 5·× 109 Am−1·s−1. Composites were prepared by dispersing MNPs under sonication in a solution of PLLA. The heat released by the MNPs was monitored by an infrared camera and changes in the polymer were analyzed with differential scanning calorimetry and nanoindentation techniques. The crystallinity, hardness, and elastic modulus of nanocomposites increase with EMF treatment.
Databáze: Directory of Open Access Journals
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