Mitochondrial dynamics quantitatively revealed by STED nanoscopy with an enhanced squaraine variant probe

Autor: Xusan Yang, Zhigang Yang, Zhaoyang Wu, Ying He, Chunyan Shan, Peiyuan Chai, Chenshuo Ma, Mi Tian, Junlin Teng, Dayong Jin, Wei Yan, Pintu Das, Junle Qu, Peng Xi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-17546-1
Popis: Live cell imaging of mitochondrial cristae is challenged by the unsuitability of current fluorescent probes and high phototoxicity. Here the authors develop a squarine variant probe (MitoESq-635) that is capable of longitudinal imaging of cristae with STED with minimal phototoxicity.
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