FLAVANONES FROM THE WOOD OF Morus nigra WITH CYTOTOXIC ACTIVITY

Autor:	Ferlinahayati Ferlinahayati, Yana Maolana Syah, Lia Dewi Juliawaty, Euis Holisotan Hakim
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	norartocarpanone euchrenone a7 Morus nigra cytotoxic Chemistry QD1-999
Zdroj:	Indonesian Journal of Chemistry, Vol 13, Iss 3, Pp 205-208 (2013)
Druh dokumentu:	article
ISSN:	1411-9420 2460-1578
DOI:	10.22146/ijc.21277
Popis:	Two flavanone derivatives, norartocarpanone (1) and euchrenone a7 (2) had been isolated for the first time from the methanol extract of the wood of Morus nigra. The structures of these compounds were determined base on spectral evidence, including UV, IR, and NMR. The first compound also confirmed by comparison with the reported data. Cytotoxic properties of these compounds were evaluated against murine leukemia P-388 cells. Euchrenone a7 (2) was found more cytotoxic than norartocarpanone (1) with their IC50 7.8 and 12.7 mg/mL respectively.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d9ff95435e294f9f9b6b9ff2b98c36e5 Zobrazit plný text záznamu View record in DOAJ