Vascular dysfunction and the age‐related decline in critical power

Autor: Abigail Dorff, Christy Bradford, Ashley Hunsaker, Jake Atkinson, Joshua Rhees, Olivia K. Leach, Jayson R. Gifford
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Experimental Physiology, Vol 109, Iss 2, Pp 240-254 (2024)
Druh dokumentu: article
ISSN: 1469-445X
0958-0670
DOI: 10.1113/EP091571
Popis: Abstract Ageing results in lower exercise tolerance, manifested as decreased critical power (CP). We examined whether the age‐related decrease in CP occurs independently of changes in muscle mass and whether it is related to impaired vascular function. Ten older (63.1 ± 2.5 years) and 10 younger (24.4 ± 4.0 years) physically active volunteers participated. Physical activity was measured with accelerometry. Leg muscle mass was quantified with dual X‐ray absorptiometry. The CP and maximum power during a graded exercise test (PGXT) of single‐leg knee‐extension exercise were determined over the course of four visits. During a fifth visit, vascular function of the leg was assessed with passive leg movement (PLM) hyperaemia and leg blood flow and vascular conductance during knee‐extension exercise at 10 W, 20 W, slightly below CP (90% CP) and PGXT. Despite not differing in leg lean mass (P = 0.901) and physical activity (e.g., steps per day, P = 0.735), older subjects had ∼30% lower mass‐specific CP (old = 3.20 ± 0.94 W kg−1 vs. young = 4.60 ± 0.87 W kg−1; P
Databáze: Directory of Open Access Journals
Externí odkaz: