Increases in plasma corin levels following experimental myocardial infarction reflect the severity of ischemic injury.

Autor:	Dong Wang, Inna P Gladysheva, Ryan D Sullivan, Tai-Hwang M Fan, Radhika M Mehta, Ranjana Tripathi, Yao Sun, Guy L Reed
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Medicine Science
Zdroj:	PLoS ONE, Vol 13, Iss 9, p e0202571 (2018)
Druh dokumentu:	article
ISSN:	1932-6203
DOI:	10.1371/journal.pone.0202571
Popis:	Following acute myocardial infarction, clinical studies show alterations in the blood levels of corin, a cardiac-selective activator of the natriuretic peptides pro-atrial natriuretic peptide (pro-ANP) and pro-B-type natriuretic peptide (pro-BNP). However, the temporal changes in circulating and cardiac corin levels and their relationships to the severity of myocardial infarction have not been studied. The main objective of this study was to examine the relationship between cardiac and circulating corin levels and their association with cardiac systolic function and infarct size during the early phase of acute myocardial infarction (0.05), 69% (P
Databáze:	Directory of Open Access Journals
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