Analysis of Urine Podocalyxin in Type 2 Diabetes Mellitus Subjects With and Without Diabetic Nephropathy
| Autor: | Jusni Ekasari Pelu, Liong Boy Kurniawan, Yuyun Widaningsih, Alfian Zainuddin, Husaini Umar, Nurahmi Nurahmi, Theosobia Grace Orno |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Indonesian Journal of Medical Laboratory Science and Technology, Vol 5, Iss 1 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2684-6748 2656-9825 |
| DOI: | 10.33086/ijmlst.v5i1.3933 |
| Popis: | Type 2 diabetes mellitus is the most common cause of diabetes, consist from about 85% of cases. Diabetic nephropathy is a complication of diabetes mellitus in the kidneys which can end up as kidney failure. Podocalyxin (PDX) is a protein expressed in kidney podocytes that is involved in various cancers, and is also essential for kidney development. The research design was carried out using observational and cross-sectional analytic methods with total participants of 25 DM with diabetic nephropathy and 25 DM without diabetic nephropathy with a purposive probability sampling technique. This research conducted at the Endocrine Polyclinic, Clinical Pathology Laboratory, Hasanuddin University Medical Research Center (HUM-RC) Laboratory, Hasanuddin University Hospital, Makassar. The results showed that the urinary PDX level in DM subjects with nephropathy were 1.160 ng/mL and DM without nephropathy were 0.167 ng/mL (p |
| Databáze: | Directory of Open Access Journals |
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