| Autor: |
Lorenzo Di Cesare Mannelli, Fortunato Palma Esposito, Enrico Sangiovanni, Ester Pagano, Carmen Mannucci, Beatrice Polini, Carla Ghelardini, Mario Dell’Agli, Angelo Antonio Izzo, Gioacchino Calapai, Donatella de Pascale, Paola Nieri |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Pharmaceuticals, Vol 14, Iss 12, p 1329 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1424-8247 |
| DOI: |
10.3390/ph14121329 |
| Popis: |
Marine pharmacology is an exciting and growing discipline that blends blue biotechnology and natural compound pharmacology together. Several sea-derived compounds that are approved on the pharmaceutical market were discovered in sponges, marine organisms that are particularly rich in bioactive metabolites. This paper was specifically aimed at reviewing the pharmacological activities of extracts or purified compounds from marine sponges that were collected in the Mediterranean Sea, one of the most biodiverse marine habitats, filling the gap in the literature about the research of natural products from this geographical area. Findings regarding different Mediterranean sponge species were individuated, reporting consistent evidence of efficacy mainly against cancer, infections, inflammatory, and neurological disorders. The sustainable exploitation of Mediterranean sponges as pharmaceutical sources is strongly encouraged to discover new compounds. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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