HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION
| Autor: | A. N. Baikov, V. E. Tolpekin, M. A. Medvedev, E. V. Semichiev, S. D. Ivanov |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Бюллетень сибирской медицины, Vol 15, Iss 3, Pp 5-9 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1682-0363 1819-3684 |
| DOI: | 10.20538/1682-0363-2016-3-5-9 |
| Popis: | Aim. The article describes the results of an experimental study of the adaptation mechanisms of heart and transplant (cardio-pulmonary complex, CPC) in heterotopic transplantation.Materials and methods. CPC`s from recipients (8 dogs) were transplanted in left oblique-diaphragmatic sinus of donor`s (8 dogs). As a results of parallel connection transplant pre- and post-load of donor`s heart was reduces. Oxygenated blood by CPC was passed the left chambers of donor`s heart and returned to the aorta. Another part from pulmonary artery shunted to the right chamber of CPC as a result decreased systolic pressure on the right ventricle of heart. During the co-working of CPC and heart was happened synchronization.Consequently self-regulating process of circulatory system provides mechanism of adaptation in new conditions. The findings are important for understanding the effectiveness and relevance of this bilogical method of circulatory support. |
| Databáze: | Directory of Open Access Journals |
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