Human oral bioavailability and pharmacokinetics of tocotrienols from tocotrienol-rich (tocopherol-low) barley oil and palm oil formulations

Autor:	Astrid M. Drotleff, Christoph Bohnsack, Inga Schneider, Andreas Hahn, Waldemar Ternes
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	Barley extract Tocotrienol composition Vitamin E Human oral bioavailability Blood plasma Urinary metabolites Nutrition. Foods and food supply TX341-641
Zdroj:	Journal of Functional Foods, Vol 7, Iss , Pp 150-160 (2014)
Druh dokumentu:	article
ISSN:	1756-4646
DOI:	10.1016/j.jff.2014.01.001
Popis:	Tocotrienols are members of the vitamin E family thought to have hypocholesterolaemic, anti-cancer, and neuroprotective properties. We compared the bioavailability and pharmacokinetics of a single oral dose of 450 mg total tocotrienols from α-tocotrienol-rich barley oil and γ-tocotrienol-rich palm oil (both also low in tocopherols) in seven healthy male human subjects 0–24 h post-dose. The maximum α-tocotrienol plasma concentration (22.57 ± 2.84 mg/L, 2.1 ± 0.3 h) was significantly (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9fa2435e61c445209fcaa8ac32946f9c Zobrazit plný text záznamu Full Text from ScienceDirect View record in DOAJ