Reconstituting the complete biosynthesis of D-lysergic acid in yeast

Autor: Garrett Wong, Li Rong Lim, Yong Quan Tan, Maybelle Kho Go, David J. Bell, Paul S. Freemont, Wen Shan Yew
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-28386-6
Popis: The ergot alkaloids are a class of natural products known for their pharmacologically privileged molecular structure that are used in the treatment of neurological ailments. Here the authors report on the production of the ergot (fungus)-derived therapeutic precursor, D-lysergic acid (DLA), in baker’s yeast.
Databáze: Directory of Open Access Journals