Association of combined −344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population

Autor: Nouhi Youssef, Aboubakr Fatima-Zahrae, Brini Otmane El, Benazzouz Bouchra, Akhouayri Omar
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Romanian Journal of Internal Medicine, Vol 62, Iss 3, Pp 323-330 (2024)
Druh dokumentu: article
ISSN: 2501-062X
DOI: 10.2478/rjim-2024-0011
Popis: Background: Aldosterone synthase (CYP11B2) is crucial for aldosterone production, and variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This study explores the link between two single nucleotide polymorphisms (SNPs) in the CYP11B2 gene - −344T/C and K173R and T2DM in the Moroccan population .
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