Review of Anti-Hyperglycemic Effect of Tinospora crispa
| Autor: | Theerawut KLANGJAREONCHAI, Supanee PUTADECHAKUM, Chulaporn ROONGPISUTHIPONG |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Walailak Journal of Science and Technology, Vol 12, Iss 5, Pp 403-406 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1686-3933 2228-835X |
| Popis: | Tinospora crispa (Borapet or Wan kab hoi yai) is a climbing plant belonging to family Menispermaceae. In traditional medicine, an extract from the stems of T. crispa has been used for anti-hyperglycemic activity. The mechanisms of the anti-hyperglycemic actions of T. crispa are due to the stimulation of insulin secretion, enhancement of glucose utilization in peripheral tissues and reduction of hepatic gluconeogenesis. Borapetoside A and C are active ingredients for lower plasma glucose. In human studies, T. crispa extract possesses a significant anti-hyperglycemic effect in metabolic syndrome but this effect is abolished in type 2 diabetes mellitus. More clinical studies are recommended to evaluate the beneficial effect of T. crispa in human models. |
| Databáze: | Directory of Open Access Journals |
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