Treatment of highly fatal extensive childhood mucormycosis with complications: A success story
| Autor: | Aakash Chandran Chidambaram, Jaikumar Govindaswamy Ramamoorthy, Reena Gulati, Bhawana A Badhe |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Indian Pediatrics Case Reports, Vol 1, Iss 2, Pp 99-101 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2772-5170 2772-5189 |
| DOI: | 10.4103/ipcares.ipcares_50_21 |
| Popis: | Background: Mucormycosis is a highly fatal infection that affects immunocompromised individuals. Treatment is difficult and mortality is high when associated with complications. It is rare as a presenting feature of diabetes mellitus (DM) in children. Clinical Description: We describe a child who presented with extensive rhino-orbital invasive mucormycosis and subsequently diagnosed as Type 1 DM. She further developed cavernous sinus thrombosis and internal carotid artery thrombosis known to be associated with very high risk of mortality. Management: Aggressive medical management with posaconazole and liposomal amphotericin B for 12 weeks and early debridement of orbito-cerebral lesions led to complete resolution. Conclusion: Saving children with complicated extensive invasive mucormycosis is possible with aggressive prolonged antifungal therapy and early debridement of lesions. |
| Databáze: | Directory of Open Access Journals |
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