Outcome of Couples with Reciprocal Translocation Carrier Undergoing the First Preimplantation Genetic Testing Cycles

Autor: Cai-Xia Lei, Shuo Zhang, Hai-Yan Sun, Sai-Juan Zhu, Jing Zhou, Jing Fu, Yi-Juan Sun, Jun-Ping Wu, Yue-Ping Zhang, Xiao-Xi Sun
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Reproductive and Developmental Medicine, Vol 2, Iss 1, Pp 30-37 (2018)
Druh dokumentu: article
ISSN: 2096-2924
DOI: 10.4103/2096-2924.232873
Popis: Background: Reciprocal translocation (RCP) causes male infertility and female recurrent pregnancy loss. Male and female carriers have different responses to meiotic disturbances. Gender difference in outcomes of the RCP couples undergoing preimplantation genetic testing (PGT) is unknown. Methods: We conducted a retrospective analysis of 238 RCP couples (124 female and 114 male carriers) divided by gender of carrier from March 2014 to March 2017. Blastocysts were divided by day 5 and day 6. Females were divided into older (≥38 years) and younger (
Databáze: Directory of Open Access Journals