Diagnostic Accuracy of Lactate Dehydrogenase/Adenosine Deaminase Ratio in Differentiating Tuberculous and Parapneumonic Effusions: A Systematic Review

Autor:	Larry Ellee Nyanti, Muhammad Aklil Abd Rahim, Nai-Chien Huan
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	lactate dehydrogenase adenosine deaminase tuberculous pleural effusion parapneumonic effusion diagnostic accuracy Diseases of the respiratory system RC705-779
Zdroj:	Tuberculosis and Respiratory Diseases, Vol 87, Iss 1, Pp 91-99 (2024)
Druh dokumentu:	article
ISSN:	1738-3536 2005-6184
DOI:	10.4046/trd.2023.0107
Popis:	Background Tuberculous pleural effusion (TPE) and parapneumonic effusion (PPE) are often difficult to differentiate owing to the overlapping clinical features. Observational studies demonstrate that the ratio of lactate dehydrogenase to adenosine deaminase (LDH/ADA) is lower in TPE compared to PPE, but integrated analysis is warranted. Methods We conducted a systematic review to evaluate the diagnostic accuracy of the LDH/ADA ratio in differentiating TPE and PPE. We explored the PubMed and Scopus databases for studies evaluating the LDH/ADA ratio in differentiating TPE and PPE. Results From a yield of 110 studies, five were included for systematic review. The cutoff value for the LDH/ADA ratio in TPE ranged from
Databáze:	Directory of Open Access Journals
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