Efficacy of aloe vera, amlexanox (5%), and triamcinolone acetonide (0.1%) in the management of oral lichen planus

Autor: Manpreet Kaur, Prerna Gulati, Sugandha Verma, Parul Khare, Ruchi Garg, Jahnobi Dutta, Kumuda Rao
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 5, Pp 133-135 (2024)
Druh dokumentu: article
ISSN: 0975-7406
DOI: 10.4103/jpbs.jpbs_416_23
Popis: Objective: This research assessed the efficiencies of aloe vera, 0.1% triamcinolone acetonide, and 5% amlexanox in the management of OLP. Materials and Methods: A total of 120 participants diagnosed with oral lichen planus (OLP) were equally divided into three groups and treated with: aloe vera, (Group A), 0.1% triamcinolone acetonide (Group B), and 5% amlexanox (Group C) topical medicaments. The patients were evaluated for pain, using the visual analogue scale (VAS). They were also evaluated for ulcerative lesion type and erosive area on days 1, 7, and 15 of the study. Results: There was a statistically considerable decrease in the VAS pain scale score, reduction in the erosive area on buccal mucosa, and healing of ulcer from day 1st to 15th day with all three tested drugs. Conclusion: All drugs used in this study; aloe vera, triamcinolone acetonide, and amlexanox were effective in treating OLP patients.
Databáze: Directory of Open Access Journals
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