| Autor: |
Morgan J. Schaeffer, Noaah Reaume, Meng Wang, Arooj Aftab, Alexander Pan, Sana Tariq, Meaghan Reid, Eric E. Smith, Chris D'Esterre, Philip A. Barber |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100177- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-2450 |
| DOI: |
10.1016/j.cccb.2023.100177 |
| Popis: |
Introduction: Transient ischaemic attack (TIA) is associated with increased risk of cognitive decline and dementia as early as one-year post-event. Regional brain atrophy measurements may predict future cognitive decline. Aims: 1) To determine whether Medial Temporal Atrophy (MTA) scores and interseptal distance (ISD) measurements are greater in patients with TIA compared to controls; and 2) To determine whether MTA and ISD predicts cognitive change one year after TIA. Methods: Baseline demographic, vascular risk factors, structural imaging and cognitive tests scores were compared between 103 Patients with TIA and 103 age-and-sex-matched controls from the Predementia Neuroimaging of Transient Ischaemic Attack (PREVENT) Study. MTA was assessed using the Schelten's Scale, and ISD was calculated as the distance between the septal nucleus of each hemisphere. Multiple linear regression models were used to evaluate how MTA and ISD related to cognitive change after adjusting for covariates. Results: Patients with TIA had larger ISD measurements (1.4 mm [SD=1.2] vs. 0.9 mm [SD=1.0]); p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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