Computer‐based evaluation of Alzheimer's disease and mild cognitive impairment patients during a picture description task

Autor: Laura Hernández‐Domínguez, Sylvie Ratté, Gerardo Sierra‐Martínez, Andrés Roche‐Bergua
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 260-268 (2018)
Druh dokumentu: article
ISSN: 2352-8729
DOI: 10.1016/j.dadm.2018.02.004
Popis: Abstract Introduction We present a methodology to automatically evaluate the performance of patients during picture description tasks. Methods Transcriptions and audio recordings of the Cookie Theft picture description task were used. With 25 healthy elderly control (HC) samples and an information coverage measure, we automatically generated a population‐specific referent. We then assessed 517 transcriptions (257 Alzheimer's disease [AD], 217 HC, and 43 mild cognitively impaired samples) according to their informativeness and pertinence against this referent. We extracted linguistic and phonetic metrics which previous literature correlated to early‐stage AD. We trained two learners to distinguish HCs from cognitively impaired individuals. Results Our measures significantly (P
Databáze: Directory of Open Access Journals