Evaluation of Osteoblastic Differentiation Induced by Microtextured Titanium Surface Produced by Laser Metal Fusion 3D Printing

Autor:	Helena Bacha Lopes, Thiago Leonardo Rios, Letícia Faustino Adolpho, Alann Thaffarell Portilho de Souza, Ulisses Moreira de Andrade Lopes, Eduardo Henrique Backes, Luiz Antonio Pessan, Gileade Pereira Freitas
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Titanium dental implant surface 3D printing laser metal fusion acid etched osteoblastic differentiation Materials of engineering and construction. Mechanics of materials TA401-492
Zdroj:	Materials Research, Vol 27 (2024)
Druh dokumentu:	article
ISSN:	1516-1439 1980-5373
DOI:	10.1590/1980-5373-mr-2023-0448
Popis:	In this study, we hypothesized that microtextured titanium (Ti) surfaces produced by laser metal fusion (LMF) 3D printing may play an important role in osteoblastic differentiation of mesenchymal stem cells (MSCs). For that, MSCs derived from mouse bone marrow were cultured on Ti discs produced in two different ways: microtextured produced by acid etched (Ti-Ac, control group) and microtextured produced by LMF 3D printing (Ti-3D-LMF, test group), in which it was evaluated: (1) cell proliferation, (2) alkaline phosphatase activity and (3) extracellular matrix mineralization. The results showed that both groups allowed cell proliferation over time (p
Databáze:	Directory of Open Access Journals
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