Autor: |
Hafeez Aderinsayo Adekola, Olajide Olubunmi Agbede, Idris Nasir Abdullahi, Lawal O. Olayemi, Anthony Uchenna Emeribe, Amos Dangana, Thairu Yunusa |
Jazyk: |
English<br />Italian |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Microbiologia Medica, Vol 34, Iss 2 (2019) |
Druh dokumentu: |
article |
ISSN: |
2280-6423 |
DOI: |
10.4081/mm.2019.8158 |
Popis: |
Invasive pulmonary aspergillosis still constitutes a diagnostic challenge for clinicians due to its non-specific symptoms. HIV infection represents one of the major risk factors due to the progressive failure of the immune system. In this study, Aspergillus serum galactomannan enzyme linked immunosorbent assay was used for the diagnosis of invasive pulmonary aspergillosis in patients living with HIV/AIDS attending University of Ilorin Teaching Hospital Antiretroviral Therapy Clinic, Nigeria. Blood samples were collected from 97 patients affected by HIV/AIDS. Age range of the study population was between 0 and 79 years. Length of the study: 3 weeks. Three out of the 97 samples were positive for the galactomannan assay with an optical density index of 1.1, 0.9 and 1.1 using the 0.5 cut-off optical density value; the concentration level of galactomannan antigen was therefore 2.20 μg/L, 1 μg/L and 2.19 μg/L, respectively. A prevalence of 3.1 % (3/97) was detected; all positive participants have been on ART for more than 3 years (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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