| Autor: |
Arash Fattahi, Pooya Afaghi, Khashayar Ghandi |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Catalysts, Vol 11, Iss 2, p 191 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2073-4344 |
| DOI: |
10.3390/catal11020191 |
| Popis: |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global threat to human health and the economy. Society needs inexpensive, fast, and accurate quantitative diagnostic tools. Here, we report a new approach using a solid-state biosensor to measure antibodies, which does not require functionalization, unlike conventional biosensors. A nanostructured semiconductor surface with catalytic properties was used as a transducer for rapid immobilization and measurement of the antibody. The transducer response was based on solid-state electronics properties. The changes on the surface of the semiconductor induced changes in the direct current (DC) surface resistivity. This was a result of a catalytic chemical reaction on that surface. This new low-cost approach reduced the response time of the measurement significantly, and it required only a very small amount of sample on the microliter scale. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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